Therapeutic Area

aCROss ICU

From Sepsis to Multi-Organ Support - Critical Care Trials With Rigor

Discuss Your Study

ICU and critical care trials involve acutely ill, often mechanically ventilated patients, complex consent processes and endpoints measured in hours, not months - every protocol detail matters.

aCROss Medical partners with Level 1 ICU centers and experienced intensivists across our four countries, delivering critical care studies with the safety oversight and rapid response these programs demand.

Our Subspecialties

Every Subspecialty Has Its Challenges. We Know Them All.

Sepsis & Septic Shock
Early-recognition protocols, novel antimicrobials and immunomodulatory therapies.
ARDS & Respiratory Failure
Mechanical ventilation strategies, ECMO and novel respiratory support devices.
Hemodynamic Monitoring & Support
Vasopressor protocols, cardiac output monitoring and shock resuscitation.
Multi-Organ Support
Renal replacement therapy, acute kidney injury and multi-organ failure studies.
Post-Surgical Critical Care
Post-operative monitoring, complication management and recovery protocols.
Sedation & Delirium Management
Sedation protocols, analgesia and ICU delirium prevention strategies.
Why aCROss

What Sets Us Apart in ICU

Intensivist-Led

Medical monitors and investigators with hands-on critical care experience.

Level 1 ICU Centers

Partnerships with high-acuity ICUs equipped for complex critical care research.

Complex Consent Expertise

Experience navigating surrogate consent and time-critical enrollment windows.

Rapid Enrollment

High-acuity patient volumes supporting time-sensitive critical care protocols.

Safety-First Approach

Round-the-clock safety monitoring built for the acuity of ICU patient populations.

Explore

Other Therapeutic Areas

Cardiology Ophthalmology Orthopaedics Neurology Urology
ATMPs OBGYN General Surgery Infectious Disease
Oncology Respiratory Vascular Dental
View our published trials →

Let's Talk About Your ICU Study

Whether you're developing a novel sepsis therapy, a respiratory support device, or a critical care monitoring platform - we'd love to hear about your program.

Discuss Your Study